58. Alternative therapies in management of Diabetes

Diabetes mellitus is a metabolic disorder in the endocrine system. This dreadful disease is found in all parts of the world and becoming a serious threat of mankind health. There are lots of chemical agents available to control and to treat diabetic ...

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Improve Cardiac Substrate Utilization

In Type 2 diabetes mellitus (T2DM) there is a more than 2-fold greater risk of developing heart failure (HF) and a 60%–80% greater probability of death in those with established HF. Evidence suggests that T2DM itself can drive adverse cardiac remod...

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Improve Mitochondrial Function and Biogenesis

Mitochondria are energy producing organelles inside each human cell. They are bacteria like structures which have their own genetic material or DNA, RNA and protein synthesizing systems. Just like bacteria they can divide on their own (fission) and a...

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Regulate Metabolic Pathways and Hormones

Several mediators are thought to signal the pancreatic Beta cells to respond to insulin resistance. These potential signaling mediators include glucose, free fatty acids, autonomic nerves, fat-derived hormones (Adiponectin), and the gut hormone gluca...

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Reduce IR and Save Beta Cells

Insulin resistance, inadequate insulin secretion, hormonal imbalances, stress and mitochondrial dysfunction play an important role in the pathogenesis of all form of Diabetes. Insulin Resistance results from inherited and acquired influences. Heredi...

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Why Beta Cells need to be saved? Very early !!

Diabetes results from a deficiency or functional impairment of insulin producing Beta cells, alone or in combination with insulin resistance (IR). The replacement or regeneration of Beta cells in humans and rodents has great promise in reversing diab...

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Repair of Beta Cells

Enhancing endogenous antioxidant and repair systems There are approximately a 100 trillion cells in the adult human body. Each cell has the same genetic code, common to all humans, much like the hardware in our computer. All of us started as one em...

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Beta Cell Mass and it’s relation to Diabetes

Beta cells in the pancreatic islets of Langerhans produce insulin. Deficiency in either beta cell mass or function, or both, can lead to insufficient level of insulin resulting in hyperglycemia (excessive levels of glucose in the blood) and diabetes....

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